Which medications in the drug class Alpha Agonists, Ophthalmic are used in the treatment of Juvenile Glaucoma?

Updated: Jun 25, 2020
  • Author: Andrew A Dahl, MD, FACS; Chief Editor: Hampton Roy, Sr, MD  more...
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Alpha Agonists, Ophthalmic

Alpha agonists work to both decrease production of fluid and increase drainage.

Brimonidine (Alphagan P)

Brimonidine is a relatively selective alpha2 adrenergic-receptor agonist that decreases IOP by dual mechanisms, reducing aqueous humor production and increasing uveoscleral outflow. Brimonidine has minimal effect on cardiovascular and pulmonary parameters. A moderate risk of allergic response to this drug exists. Caution should be used in individuals who have developed an allergy to Iopidine. IOP lowering of up to 27% has been reported. Applied topically 2-3 times a day.

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