What is the role of juvenile xanthogranuloma in the etiology of glaucoma?

Updated: Jun 25, 2020
  • Author: Andrew A Dahl, MD, FACS; Chief Editor: Hampton Roy, Sr, MD  more...
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Answer

Juvenile xanthogranuloma is a benign histiocytic tumor affecting the skin and eye in young children. A salmon colored iris tumor is associated with spontaneous hyphema in children. Glaucoma results from direct obstruction of the outflow tract by histiocytes or outflow obstruction secondary to hyphema. Radiation therapy to the iris tissue has helped to resolve the iris tumor and glaucoma.


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