Which medications in the drug class Prostaglandin analogs are used in the treatment of Hyphema Glaucoma?

Updated: Jul 29, 2020
  • Author: Inci Irak Dersu, MD, MPH; Chief Editor: Hampton Roy, Sr, MD  more...
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Answer

Prostaglandin analogs

These selective agonists act on prostaglandin receptors in the eye to lower IOP by increasing uveoscleral outflow. In hyphema, possible increased inflammation associated with this class of medicines should be kept in mind. In addition, the IOP lowering effect may take longer than with other classes of antiglaucoma medications.

Bimatoprost ophthalmic solution (Lumigan, Latisse, Durysta)

A prostamide analogue with ocular hypotensive activity. Mimics the IOP-lowering activity of prostamides via the prostamide pathway. Used to reduce IOP in open-angle glaucoma or ocular hypertension.

Travoprost ophthalmic solution (Travatan Z)

Prostaglandin F2-alpha analog. Selective FP prostanoid receptor agonist believed to reduce IOP by increasing uveoscleral outflow. Used to treat open-angle glaucoma or ocular hypertension.

Latanoprost (Xalatan, Xelpros)

Latanoprost may decrease IOP by increasing the outflow of aqueous humor. Patients should be informed about possible cosmetic effects to the eye/eyelashes, especially if uniocular therapy is to be initiated.

Latanoprostene bunod ophthalmic (Vyzulta)

Metabolized into latanoprost acid in the eye. Enhances conventional trabecular uveoscleral outflow of aqueous humor.


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