What are the treatment options for mild-to-moderate Graves ophthalmopathy?

Updated: Mar 23, 2018
  • Author: Sai-Ching Jim Yeung, MD, PhD, FACP; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Answer

For mild-to-moderate ophthalmopathy, local therapeutic measures (eg, artificial tears and ointments, sunglasses, eye patches, nocturnal taping of the eyes, prisms, elevating the head at night) can control symptoms and signs. If the disease is active, the mainstays of therapy are (1) high-dose glucocorticoids, [57] (2) orbital radiotherapy, (3) both, or (4) orbital decompression. [58] A meta-analysis has shown that a 3-month course of prednisone (0.4-0.5 mg/kg) reduced the progression of preexisting mild-to-moderate ophthalmopathy. [53]


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