Which medications are used in the treatment of primary open-angle glaucoma (POAG)?

Updated: Mar 16, 2020
  • Author: Kristin Schmid Biggerstaff, MD; Chief Editor: Inci Irak Dersu, MD, MPH  more...
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Answer

Medications used in the management of primary open-angle glaucoma include the following:

  • Beta-adrenergic blockers (eg, levobunolol, timolol, carteolol, betaxolol, metipranolol, levobetaxolol)
  • Adrenergic agonists (eg, brimonidine, apraclonidine)
  • Less-selective sympathomimetics (eg, dipivefrin, epinephrine)
  • Carbonic anhydrase inhibitors (eg, dorzolamide, brinzolamide, acetazolamide, methazolamide)
  • Prostaglandin analogs (eg, latanoprost, bimatoprost, travoprost, tafluprost, latanoprostene bunod)
  • Miotic agents (eg, pilocarpine)
  • Hyperosmotic agents (eg, isosorbide dinitrate, mannitol, glycerin)
  • Beta-blocker/alpha agonist combination (eg, brimonidine/timolol)
  • Beta-blocker/carbonic anhydrase inhibitor combination (eg, dorzolamide/timolol)
  • Alpha agonist/carbonic anhydrase inhibitor (eg, brimonidine/brinzolamide)

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