What is the role of lab testing in the diagnosis of primary open-angle glaucoma (POAG)?

Updated: Mar 16, 2020
  • Author: Kristin Schmid Biggerstaff, MD; Chief Editor: Inci Irak Dersu, MD, MPH  more...
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Laboratory tests that may be used to rule other causes for optic neuropathy in patients suspected of having normal-tension glaucoma include the following:

  • CBC count
  • Erythrocyte sedimentation rate
  • Serology for syphilis (micro-hemagglutination- Treponema pallidum [MHA-TP], not Venereal Disease Research Laboratory [VDRL] test)
  • Rarely, serum protein electrophoresis: For individuals with potential autoimmune etiology for some glaucomatous optic neuropathies

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