What is the role of cycloplegics in the treatment of human leukocyte antigen (HLA) B27–associated acute anterior uveitis (AAU)?

Updated: Oct 30, 2018
  • Author: Anna Luisa Di Lorenzo, MBBCh; Chief Editor: Andrew A Dahl, MD, FACS  more...
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Cycloplegics help relieve photophobia, secondary to ciliary spasm, and prevent and break synechiae formation. In most cases, short-acting drops, such as 1% cyclopentolate hydrochloride or 1% tropicamide, are sufficient. These allow pupillary motility and rapid recovery when discontinued. Longer acting cycloplegics, such as 5% homatropine, 0.25% scopolamine, and 1% atropine may also be useful. If the uveitis is more severe, more frequent dosing of cycloplegics may be necessary.

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