Which medications in the drug class Anticonvulsants are used in the treatment of Congenital Nystagmus (Infantile Nystagmus)?

Updated: Oct 08, 2019
  • Author: Mark Ventocilla, OD, FAAO; Chief Editor: Edsel Ing, MD, MPH, FRCSC  more...
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Answer

Anticonvulsants

Agents acting through gabapentin binding sites that may activate voltage-gated calcium channels may be useful in treating nystagmus.

Gabapentin (Neurontin)

Has been shown to be useful in some adults with congenital nystagmus in improving symptoms. No studies have been done in children to date. Exact mechanism of action is unknown but thought to be due to its antiglutamatergic activity. Has been used successfully to treat adult acquired nystagmus in multiple sclerosis.


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