What is the role of CD8+ T cells in Stevens-Johnson syndrome (SJS)?

Updated: Jan 17, 2019
  • Author: C Stephen Foster, MD, FACS, FACR, FAAO, FARVO; Chief Editor: Andrew A Dahl, MD, FACS  more...
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Answer

CD8+ T cells that recognize major histocompatibility complex I (MHC-I) modified by an antigen may produce skin lesions of Stevens-Johnson syndrome, or they may be produced by T cells that recognize an antigen that is restricted by MHC-I


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