Which ocular signs may be noted on slit-lamp exam in Stevens-Johnson syndrome (SJS)?

Updated: Jan 17, 2019
  • Author: C Stephen Foster, MD, FACS, FACR, FAAO, FARVO; Chief Editor: Andrew A Dahl, MD, FACS  more...
  • Print
Answer

The following ocular signs may be noted on slit lamp examination (see the images below):

  • Eyelids: Trichiasis, distichiasis, meibomian gland dysfunction, blepharitis

  • Conjunctiva: Papillae, follicles, keratinization, subepithelial fibrosis, conjunctival shrinkage, foreshortening of fornices, symblepharon, ankyloblepharon

  • Cornea: Superficial punctate keratitis, epithelial defect, stromal ulcer, neovascularization, keratinization, limbitis, conjunctivalization, stromal opacity, perforation

    A patient with severe eye involvement associated w A patient with severe eye involvement associated with Stevens-Johnson syndrome. Note corneal neovascularization and conjunctivalization of the ocular surface.
    Epithelial defect of the cornea with neovasculariz Epithelial defect of the cornea with neovascularization and surface conjunctivalization.

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!