Can a diagnosis of Stevens-Johnson syndrome (SJS) be established in the absence of skin lesions?

Updated: Jan 17, 2019
  • Author: C Stephen Foster, MD, FACS, FACR, FAAO, FARVO; Chief Editor: Andrew A Dahl, MD, FACS  more...
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Answer

Although some have suggested the possibility of Stevens-Johnson syndrome without skin lesions, most believe that mucosal lesions alone are not enough to establish the diagnosis. Cases without skin lesions have been termed "atypical" or "incomplete." [17] These authors suggested that the combination of urethritis, conjunctivitis, and stomatitis established the diagnosis of Stevens-Johnson syndrome in a patient with Mycoplasma pneumonia– induced signs and symptoms.


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