What long-term complications are associated with Stevens-Johnson syndrome (SJS)?

Updated: Jan 17, 2019
  • Author: C Stephen Foster, MD, FACS, FACR, FAAO, FARVO; Chief Editor: Andrew A Dahl, MD, FACS  more...
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Answer

Survivors of Stevens-Johnson syndrome may experience numerous long-term sequelae; the most disabling are those of the eye. Cicatrization of conjunctival erosions may lead to the following:

  • Inverted eyelashes
  • Photophobia
  • A burning sensation in the eyes
  • Watery eyes
  • A keratitis siccalike syndrome
  • Corneal and conjunctival neovascularization

As many as 40% of survivors of toxic epidermal necrolysis have residual potentially disabling lesions that may cause blindness.


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