Which anticonvulsants may cause Stevens-Johnson syndrome (SJS)?

Updated: Jan 17, 2019
  • Author: C Stephen Foster, MD, FACS, FACR, FAAO, FARVO; Chief Editor: Andrew A Dahl, MD, FACS  more...
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Answer

The following anticonvulsants have been implicated:

  • Phenytoin
  • Carbamazepine
  • oxcarbazepine (Trileptal)
  • Valproic acid
  • Lamotrigine
  • Barbiturates

Mockenhaupt et al stressed that most anticonvulsant-induced SJS occurs in the first 60 days of use. [20]


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