Which procedure is needed to establish a definitive diagnosis of Stevens-Johnson syndrome (SJS) and how is it treated?

Updated: Jan 17, 2019
  • Author: C Stephen Foster, MD, FACS, FACR, FAAO, FARVO; Chief Editor: Andrew A Dahl, MD, FACS  more...
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There are no specific laboratory studies (other than biopsy) that can definitively establish the diagnosis of Stevens-Johnson syndrome (see Clinical and Workup). No specific treatment of Stevens-Johnson syndrome is noted; most patients are treated symptomatically. In principle, the symptomatic treatment of patients with Stevens-Johnson syndrome does not differ from the treatment of patients with extensive burns. Withdrawal of the suspected offending agent is critically important. Immunomodulatory treatment is controversial. (See Treatment.)

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