What are the ocular exam findings in Stevens-Johnson syndrome (SJS)?

Updated: Jan 17, 2019
  • Author: C Stephen Foster, MD, FACS, FACR, FAAO, FARVO; Chief Editor: Andrew A Dahl, MD, FACS  more...
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Answer

Ocular examination can demonstrate the following:

  • Conjunctival biopsies from patients with active ocular disease show subepithelial plasma cells and lymphocyte infiltration; lymphocytes also are present around vessel walls; the predominant infiltrating lymphocyte is the helper T cell

  • Immunohistology of the conjunctiva reveals numerous HLA-DR–positive cells in the substantia propria, vessel walls, and epithelium

See Workup for more detail.


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