Which medications in the drug class Antibiotics are used in the treatment of Ocular Rosacea?

Updated: Mar 03, 2020
  • Author: Jitander Dudee, MD, MA(Cantab), FACS, FRCOphth; Chief Editor: Edsel Ing, MD, MPH, FRCSC  more...
  • Print
Answer

Antibiotics

Anti-inflammatory effect helps to ameliorate meibomian gland disease.

Tetracycline

Inhibits bacterial protein synthesis by binding with 30S and possibly 50S ribosomal subunit(s). Has anti-inflammatory activity. Also a potent collagenase inhibitor.

Doxycycline (Vibramycin, Doryx, Adoxa, Alodox)

DOC; inhibits bacterial protein synthesis by binding with 30S and possibly 50S ribosomal subunit(s). Has anti-inflammatory activity. Also a potent collagenase inhibitor.

Clarithromycin (Biaxin, Biaxin XL)

Inhibits bacterial growth, possibly by blocking dissociation of peptidyl t-RNA from ribosomes causing RNA-dependent protein synthesis to arrest. Effective through secondary, anti-inflammatory action.

Metronidazole (Flagyl, MetroCream, Rosadan, Vandazole)

Has anti-inflammatory and immunosuppressive activity. Topical and systemic dosage forms have been found to be effective.

Erythromycin ophthalmic (Ilotycin)

Used to decrease meibomian gland bacterial overgrowth.

Azithromycin ophthalmic (AzaSite)

This ophthalmic macrolide antibiotic is indicated for bacterial conjunctivitis may be used off label in the treatment of meibomian gland dysfunction.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!