What causes ocular rosacea?

Updated: Mar 03, 2020
  • Author: Jitander Dudee, MD, MA(Cantab), FACS, FRCOphth; Chief Editor: Edsel Ing, MD, MPH, FRCSC  more...
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Answer

Flushing triggers: These include alcohol, hot beverages, tobacco, spicy foods, vasodilating medications, and emotional stress.

UV light: This is postulated to decrease the competence of already dilated cutaneous vasculature, increasing persistent erythema and telangiectasias.

Demodex: This mite, which is part of the skin's normal flora, leads to stimulation of the innate immune system. Bacteria in the gut of Demodex may be the inciting factor rather than the Demodex itself. [11]

S epidermidis: Hyper-reactivity of the innate immune system in rosacea patients makes them sensitive to this normal skin flora. [12]

H pylori: This is postulated to be strongly correlated with rosacea. This is possibly due to a flush-inducing toxin present in H pylori.

Positive family history: Some studies have shown a higher rate of positive family history of rosacea in patients with this dermatologic disorder than in skin-healthy controls. [18]

Smoking: Some studies have shown an increased history of smoking in patients with rosacea as compared with skin-healthy controls. [18, 19]


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