How is herpes simplex virus (HSV) endotheliitis classified?

Updated: Jan 18, 2019
  • Author: Jim C Wang (王崇安), MD; Chief Editor: Andrew A Dahl, MD, FACS  more...
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HSV endotheliitis can be classified as follows:

  • Disciform endotheliitis - Presents with a round area of corneal edema in a central or paracentral region with a clear demarcation between involved and uninvolved cornea (see the image below)

  • Diffuse endotheliitis - Shows scattered KP and may stem from a previous disciform area of involvement

  • Linear endotheliitis - Appears as a line of KP progressing centrally from the limbus, with peripheral corneal edema trailing the migrating line of KP; the line of KP can be sectoral or circumferential and may take on either a straight or serpiginous pattern

    Disciform endotheliitis with secondary stromal cor Disciform endotheliitis with secondary stromal corneal ulceration.

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