How is immune stromal keratitis (ASK) characterized?

Updated: Jan 18, 2019
  • Author: Jim C Wang (王崇安), MD; Chief Editor: Andrew A Dahl, MD, FACS  more...
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Answer

ISK, also known as nonnecrotizing stromal keratitis and interstitial keratitis, is a common manifestation of chronic, recurrent ocular HSV disease; ISK may present clinically with focal, multifocal, or diffuse cellular infiltrates; immune rings; neovascularization of the corneal stroma; or ghost vessels at any level of the cornea. (See the images below.)

Active immune stromal keratitis. Active immune stromal keratitis.
Inactive immune stromal keratitis. Inactive immune stromal keratitis.

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