What is the prognosis of herpes simplex virus (HSV) keratitis?

Updated: Jan 18, 2019
  • Author: Jim C Wang (王崇安), MD; Chief Editor: Andrew A Dahl, MD, FACS  more...
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HSV keratitis is the most frequent cause of corneal blindness in the United States and is a leading indication for corneal transplantation. It is also the most common cause of infectious blindness in the Western world.

The prognosis in HSV keratitis is generally favorable with aggressive treatment. Even with proper therapy, however, corneal scarring can occur. If the scarring develops centrally, visual acuity can be lost.

Stromal keratitis

Significant anterior chamber inflammation may accompany stromal keratitis. Permanent stromal scarring may lead to profound visual loss. In addition, all stromal keratitis types may develop uveitis, trabeculitis, and secondary glaucoma.

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