How is conjunctival melanoma treated?

Updated: Feb 16, 2021
  • Author: Manolette R Roque, MD, MBA, FPAO; Chief Editor: Hampton Roy, Sr, MD  more...
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Mitomycin is an off-label drug that is used in ophthalmology. It is a potent chemotherapeutic agent that inhibits fibroblasts and, therefore, diminishes scarring after glaucoma filtering surgery. It has been used as an adjunct in pterygium surgery, photorefractive keratoplasty haze management, and conjunctival melanoma management. (Applied topically, however, mitomycin-C has reportedly resulted in an intumescent lens, requiring surgical intervention.) [26, 27]

Outpatient radiotherapy is indicated as needed in patients with conjunctival melanoma. [28]

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