What is the role of liver enzyme tests in the workup of choroidal melanoma?

Updated: Feb 18, 2020
  • Author: Enrique Garcia-Valenzuela, MD, PhD; Chief Editor: Andrew A Dahl, MD, FACS  more...
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Liver enzyme levels are indicated in any patient with uveal melanoma, because the liver is the most common site of choroidal melanoma metastasis. The most sensitive tests of hepatic function are serum levels of the following:

  • Alkaline phosphatase

  • Glutamic-oxaloacetic transaminase

  • Lactate dehydrogenase

  • Gamma-glutamyl transpeptidase

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