What is the role of bariatric surgery in the treatment of glucose intolerance disorders?

Updated: Jun 28, 2019
  • Author: Samuel T Olatunbosun, MD, FACP, FACE; Chief Editor: George T Griffing, MD  more...
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Bariatric surgery should be considered in a patient with type 2 diabetes who has a BMI of more than 35 kg/m2, especially if glycemic control with lifestyle and pharmacotherapy is difficult. [1] Surgically induced weight loss may result in improvements in insulin sensitivity and beta-cell function, as well as changes in gut hormones. [64, 65] Better diabetic control or complete resolution of the disease (64-93%) is the end result.

A bariatric procedure is not currently recommended in the management of IGT or IFG; however, glucose intolerance resolved in 99-100% of cases of patients who underwent bariatric surgery for a comorbid state that required such an intervention (eg, class 3 obesity).

Long-term support and medical monitoring are still important after a bariatric procedure. Various complications, including postprandial hyperinsulinemic hypoglycemia, have been reported following gastric bypass surgery.

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