Which clinical history findings are characteristic of prediabetes?

Updated: Jul 08, 2020
  • Author: Samuel T Olatunbosun, MD, FACP, FACE; Chief Editor: George T Griffing, MD  more...
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Answer

The categories of impaired glucose tolerance (IGT) and impaired fasting glucose (IFG) have been officially termed prediabetes, because they are risk factors for future diabetes and for cardiovascular disease. [41, 42] However, the World Health Organization (WHO) recommends the term intermediate hyperglycemia, noting that prediabetes does not always progress to diabetes as the term implies and the focus on diabetes may divert attention from the significantly increased cardiovascular risk. [3]

Most cases of IGT and IFG are diagnosed when the presence of one or more cardiovascular risk factors necessitates the need to screen for a disorder of glucose tolerance.

Patients with impaired glucose homeostasis are generally asymptomatic. Features of related risk factors for cardiovascular disease may be present, even with a mild degree of hyperglycemia. They include a history of hypertension, obesity, dyslipidemia, and/or macrovascular disease, such as stroke, coronary disease, or peripheral vascular disease.


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