Which medications in the drug class Orexin Receptor Antagonists are used in the treatment of Sleep Dysfunction in Women?

Updated: Jan 31, 2019
  • Author: Gila Hertz, PhD, ABSM; Chief Editor: Selim R Benbadis, MD  more...
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Answer

Orexin Receptor Antagonists

Agents in this class block the binding of wake-promoting neuropeptides orexin A and orexin B to their respective receptors OX1R and OX2R, which may suppress wake drive.

Suvorexant (Belsomra)

Suvorexant is the first orexin receptor antagonist used for the treatment of insomnia. It is found to be generally safe and well tolerated by patients. Therefore, it can be used for chronic insomnia therapy.


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