What types of narcolepsy treatments are currently being investigated?

Updated: Sep 04, 2019
  • Author: Sagarika Nallu, MD; Chief Editor: Selim R Benbadis, MD  more...
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Answer

Research into future treatments is focusing on preventing the loss of hypocretin (orexin)-producing neurons by targeting the proposed autoimmune-driven mechanism of narcolepsy. Trials of intravenous (IV) immunoglobulin (IVIG) are in their infancy. Future research may also investigate the restoration of hypocretin signaling with agonists or gene therapy.


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