What medications are used in the treatment of restless legs syndrome (RLS)?

Updated: Feb 22, 2017
  • Author: Ali M Bozorg, MD; Chief Editor: Selim R Benbadis, MD  more...
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Answer

Medications used in the treatment of restless legs syndrome (RLS) include the following:

  • Dopaminergic agents (eg, pramipexole, [27] ropinirole, [28, 29] bromocriptine, levodopa-carbidopa, and rotigotine [30] )

  • Benzodiazepines (eg, clonazepam)

  • Opioids (eg, codeine)

  • Anticonvulsants (eg, gabapentin [31] and pregabalin)

  • Presynaptic alpha2 -adrenergic agonists (eg, clonidine)

  • Iron salt


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