How is vascular disease differentiated from restless legs syndrome (RLS)?

Updated: Feb 22, 2017
  • Author: Ali M Bozorg, MD; Chief Editor: Selim R Benbadis, MD  more...
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Vascular disease (including deep vein thrombosis and claudication) must be considered. Patients with RLS have intact peripheral pulses and typically do not have edema or cool extremities. Also, vascular disease does not exhibit a circadian pattern and usually worsens with activity, not with rest.

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