How is neuropathy differentiated from restless legs syndrome (RLS)?

Updated: Feb 22, 2017
  • Author: Ali M Bozorg, MD; Chief Editor: Selim R Benbadis, MD  more...
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Patients with neuropathy can have symptoms similar to those of RLS. [25] Typical sensory complaints include numbness, tingling, and pain. However, neuropathic symptoms also differ from RLS symptoms in that they usually are not associated with motor restlessness or helped by movement, nor do they worsen in the evening or at night. Neuropathy and RLS may coexist. RLS occurs more frequently in patients with hereditary neuropathies but not in patients with acquired neuropathies, such as diabetic neuropathy. [25]

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