What are the pharmacologic therapy options in the treatment of restless legs syndrome (RLS)?

Updated: Feb 22, 2017
  • Author: Ali M Bozorg, MD; Chief Editor: Selim R Benbadis, MD  more...
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Drug therapy for primary RLS is largely symptomatic, since cure is possible only in secondary disease. Medications used in the treatment of RLS include the following:

  • Dopaminergic agents

  • Benzodiazepines

  • Opioids

  • Anticonvulsants

  • Presynaptic alpha2-adrenergic agonists

  • Iron salt

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