What is the role of iron level measurement in the workup of restless legs syndrome (RLS)?

Updated: Feb 22, 2017
  • Author: Ali M Bozorg, MD; Chief Editor: Selim R Benbadis, MD  more...
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Answer

All patients with symptoms of RLS should be tested for iron deficiency. [3, 4] At a minimum, a ferritin level should be obtained, although a complete iron panel, including the following, is preferable, since ferritin can be falsely elevated in acute inflammatory states:

  • Iron levels

  • Ferritin

  • Transferrin saturation

  • Total iron binding capacity


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