What is the role of long-term hypnotic drug treatment for insomnia?

Updated: Sep 11, 2018
  • Author: Jasvinder Chawla, MD, MBA; Chief Editor: Selim R Benbadis, MD  more...
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Long-term hypnotic pharmacotherapy may be necessary in patients with severe or treatment-resistant insomnia or chronic comorbid disorders, but follow-up must include regular assessment of necessity, efficacy, and adverse effects. [1] Long-term administration of hypnotics may be intermittent, as needed, or nightly. [1] If possible, during long-term therapy, patients should receive an adequate trial of CBT. [1]

These agents should be used with caution in patients with a history of insufficient sleep syndrome, particularly in patients prone to alcohol use, since this group can be predisposed to the development of parasomnias (eg, sleep-walking or sleep-related eating disorder [83, 84] )

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