What is the mortality and morbidity associated with euthyroid sick syndrome?

Updated: Oct 08, 2018
  • Author: Serhat Aytug, MD; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Mortality and morbidity depend on the underlying NTI, the severity, and, possibly, the duration of the illness. [15, 16] The magnitude of the thyroid function test result abnormalities seems to depend on the severity, rather than the type, of illness. T4 is believed to fall in proportion to severity of illness.

The probability of death correlates with the levels of T4. When serum total T4 levels drop below 4 mcg/dL, the probability of death is about 50%; with serum T4 levels below 2 mcg/dL, the probability of death reaches 80%.

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