What is the prevalence of euthyroid sick syndrome in the US?

Updated: Oct 08, 2018
  • Author: Serhat Aytug, MD; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Answer

The frequency of thyroid function abnormalities is related to the magnitude of the illness. The most common abnormality is a T3 reduction, occurring in about 40-100% of cases of NTI, which parallels the increase of rT3. As the disease severity increases, T4 levels also decrease. Most patients who are critically ill have reduced T4 levels. In patients who are hospitalized with an NTI, about 10% have abnormally low TSH values. The highest incidence occurs among the most severely ill group.


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