What is the role of surgery in the treatment of drug-resistant epilepsy?

Updated: May 30, 2019
  • Author: David Y Ko, MD; Chief Editor: Selim R Benbadis, MD  more...
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Although surgery for drug-resistant epilepsy is often considered a last resort, results of a multicenter trial suggested that early surgery may be helpful in some patients with newly intractable and disabling temporal lobe epilepsy. In this trial, patients who had had no more than 2 consecutive years of disabling seizures refractory to adequate trials of 2 anticonvulsant medications were randomized to anteromesial temporal lobe resection plus continued medication (n = 15) or continued medication alone (n = 23). [74]

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