How is the serum antiepileptic drug (AED) trough level used in the management of epilepsy?

Updated: May 30, 2019
  • Author: David Y Ko, MD; Chief Editor: Selim R Benbadis, MD  more...
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Answer

The usual therapeutic range for an AED includes peak and trough levels measured in a group of adult patients. If a drug’s toxicity is under study, the peak level is desirable. In most circumstances, however, a trough level is the best indication of efficacy.


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