What is the role of prolactin assays in the evaluation of epileptic seizures?

Updated: May 30, 2019
  • Author: David Y Ko, MD; Chief Editor: Selim R Benbadis, MD  more...
  • Print
Answer

Historically, prolactin levels obtained shortly after a seizure (within 20 min) have been used to assess the etiology (epileptic or nonepileptic) of a spell. levels are typically elevated 3- or 4-fold, and elevations are more likely to occur with generalized tonic-clonic seizures than with other seizure types. However, not only has the considerable variability of prolactin levels precluded routine clinical use of such testing, but a baseline prolactin level is often obtained the next day at the same time as when the seizure first occurred, which makes the testing more cumbersome.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!