What causes benign familial neonatal seizures?

Updated: May 30, 2019
  • Author: David Y Ko, MD; Chief Editor: Selim R Benbadis, MD  more...
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Answer

Benign familial neonatal seizures are caused by mutations in the KCNQ2 or KCNQ3 genes and are inherited in an autosomal dominant manner. Neonates with this disorder will experience tonic-clonic seizures a few days after birth, and these seizures will remit within 1 month. Most infants will have normal development, but there is a 10-15% risk of seizure disorder later in life.


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