Which mechanisms lead to decreased neurotransmitter inhibition in epileptic seizures?

Updated: May 30, 2019
  • Author: David Y Ko, MD; Chief Editor: Selim R Benbadis, MD  more...
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Answer

Mechanisms leading to decreased inhibition include the following:

  • Defective GABA-A inhibition

  • Defective GABA-B inhibition

  • Defective activation of GABA neurons

  • Defective intracellular buffering of calcium


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