How does the pathophysiology of focal-onset epileptic seizures differ from generalized-onset epileptic seizures?

Updated: May 30, 2019
  • Author: David Y Ko, MD; Chief Editor: Selim R Benbadis, MD  more...
  • Print
Answer

The pathophysiology of focal-onset seizures differs from the mechanisms underlying generalized-onset seizures. Overall, cellular excitability is increased, but the mechanisms of synchronization appear to substantially differ between these 2 types of seizure and are therefore discussed separately. For a review, see the epilepsy book of Rho, Sankar, and Cavazos. [5] For a more recent review, see Kramer and Cash. [6]


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!