Which medications in the drug class Alpha2-Adrenergic Agonists are used in the treatment of Tourette Syndrome and Other Tic Disorders?

Updated: May 30, 2019
  • Author: William C Robertson, Jr, MD; Chief Editor: Stephen L Nelson, Jr, MD, PhD, FAACPDM, FAAN, FAAP  more...
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Alpha2-Adrenergic Agonists

These agents are used for tic suppression or for treatment of ADHD.

Clonidine (Catapres)

Clonidine is less effective than neuroleptics in suppressing tics and less effective than stimulants at treating ADHD symptoms. However, it has modest adverse effects and benefits some patients.

Guanfacine (Tenex, Intuniv)

Guanfacine has been proven to benefit ADHD and, to a lesser extent, tic severity in children with chronic tics and ADHD.

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