What is the role of ondansetron in the treatment of Tourette syndrome (TS) and other tic disorders?

Updated: May 30, 2019
  • Author: William C Robertson, Jr, MD; Chief Editor: Stephen L Nelson, Jr, MD, PhD, FAACPDM, FAAN, FAAP  more...
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Ondansetron (8-24 mg/d) showed efficacy for a self-report but not an observer-rated measure of clinical improvement in a double-blind RCT in patients aged 12-46 years with TS. [16]

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