Which medications have been used in the treatment of tics?

Updated: May 30, 2019
  • Author: William C Robertson, Jr, MD; Chief Editor: Stephen L Nelson, Jr, MD, PhD, FAACPDM, FAAN, FAAP  more...
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Treatments for tics that have not been proven in replicated RCTs include the following:

  • Guanfacine

  • Clonidine

  • Topiramate

  • Norepinephrine reuptake inhibitors

  • Botulinum toxin injections and oral baclofen

  • Tetrabenazine

  • Benzodiazepines

  • Levetiracetam

  • Selective serotonin reuptake inhibitors (SSRIs)

  • Ondansetron

  • Naltrexone/naloxone

  • Cannabinoids

  • Nicotine

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