Which findings on functional imaging are related to motor activation in the pathophysiology of Tourette syndrome (TS) and other tic disorders?

Updated: May 30, 2019
  • Author: William C Robertson, Jr, MD; Chief Editor: Stephen L Nelson, Jr, MD, PhD, FAACPDM, FAAN, FAAP  more...
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Answer

In an fMRI study, volunteers with TS performing a simple finger-tapping task had a larger activation of sensorimotor and supplementary motor area than that of control subjects. [63]

By contrast, an fMRI study of precision movement showed decreased activity of supplementary motor area in tic patients versus control subjects. [64]


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