What is the role of amphetamines in the pathophysiology of Tourette syndrome (TS)?

Updated: May 30, 2019
  • Author: William C Robertson, Jr, MD; Chief Editor: Stephen L Nelson, Jr, MD, PhD, FAACPDM, FAAN, FAAP  more...
  • Print

Singer et al demonstrated normal dopamine release at baseline in TS but altered dopamine release in response to a pharmacologic challenge with amphetamine. [40] This observation may explain the essentially normal neurologic function seen in TS when tics are not apparent.

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!