Which histologic findings are characteristic of congenital muscular dystrophy (CMD) with familial junctional epidermolysis bullosa?

Updated: Jul 03, 2019
  • Author: Emad R Noor, MBChB; Chief Editor: Amy Kao, MD  more...
  • Print
Answer

Congenital muscular dystrophy with familial junctional epdermolysis bullosa

  • Variation in muscle fiber size, internal nuclei, increased connective tissue, muscle fiber necrosis and regeneration

  • Plectin immunostaining is reduced in muscle Z-lines and skin


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!