What therapies are available to normalize preprandial and postprandial glycemia?

Updated: Sep 27, 2021
  • Author: Romesh Khardori, MD, PhD, FACP; Chief Editor: George T Griffing, MD  more...
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Intuitively, one would assume that therapies that normalize preprandial and postprandial glycemia (or that come close to normalizing them) would be optimal. Whether such a strategy can be achieved without untoward adverse effects and with further reductions in microvascular and macrovascular disease risk (compared with regimens used in the UKPDS) using newly available therapies is open to question. Practically speaking, most patients are fully occupied trying to handle conventional glucose monitoring and insulin dose adjustment.

Eating a high-protein prebreakfast snack, such as one with soy yogurt, is a simple way to achieve better postbreakfast glycemic control, according to a study by Chen et al; this study confirms a phenomenon observed in healthy humans nearly a century ago (Staub, 1921). [295]

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