How does metformin therapy impact mortality rates from heart failure in type 2 diabetes mellitus (DM)?

Updated: Oct 07, 2020
  • Author: Romesh Khardori, MD, PhD, FACP; Chief Editor: George T Griffing, MD  more...
  • Print
Answer

A retrospective, nationwide cohort study found that metformin is associated with a low risk of mortality in patients who have diabetes and experience heart failure compared with treatment that includes a sulfonylurea or insulin. [169] Roussel et al studied the expanded use of metformin in groups of patients with diabetes previously considered high risk for possible drug-related adverse outcome and found a decrease in mortality in these patients. [170]


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!