When and how should screening for microalbuminuria be performed in patients with type 2 diabetes mellitus (DM)?

Updated: Sep 27, 2021
  • Author: Romesh Khardori, MD, PhD, FACP; Chief Editor: George T Griffing, MD  more...
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Annual screening for microalbuminuria (see Microalbumin) is recommended in all patients with diabetes. Measuring the albumin-to-creatinine ratio in a spot urine sample is probably the easiest method; the ratio, expressed in mg/g, is equivalent to albumin excretion in milligrams daily. A result greater than 30 mg/g indicates albuminuria, in which case a quantitation on a timed urine specimen (ie, overnight, 10 h, or 24 h) should be performed.

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