Why isn’t the International IFCC reference method for measurement of HbA1c used in clinical practice?

Updated: Oct 23, 2019
  • Author: Romesh Khardori, MD, PhD, FACP; Chief Editor: George T Griffing, MD  more...
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Answer

The International Federation of Clinical Chemistry (IFCC) has developed a reference method for measurement of HbA1c. The IFCC method produces values lower than the HbA1c methods in current clinical use; conversion requires a complex formula. Although more accurate, the IFCC method is complicated, time consuming, and expensive. Consequently, there are no immediate plans for its adoption into clinical practice.


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